Lens Dislocation (Ectopia Lentis)
Article Sections
Introduction
Lens dislocation, or ectopia lentis, refers to displacement of the crystalline lens from its usual position within the eye. The lens is normally tethered to the ciliary body by fibrous strands known as zonular fibers. Weakening or disruption of these fibers can lead to partial or complete lens displacement. Trauma is the most common cause, but other etiologies include genetic conditions and iatrogenic injury. Poor vision is typically the first sign and a displaced lens is seen on slit lamp examination. Delays in management may lead to significant visual impairment and complications such as glaucoma or retinal detachment.
Pathogenesis and risk factors
The lens is stabilized within the eye by zonular fibers, fibrous strands of fibrillin protein that anchor the lens to the ciliary body and maintain its central position in the eye (
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